TLR4 Antibody | F51856-0.08ML

TLR4 Antibody | F51856-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This TLR4 antibody is available for research use only.

Purity: Antigen affinity

Description: TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.

Immunogen: A portion of amino acids 669-698 from the human protein was used as the immunogen for this TLR4 antibody.

Storage: Aliquot the TLR4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.