Description
TLR2 Antibody | V2896SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: TLR2/221
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: Functional studies
Buffer: N/A
Limitation: This TLR2 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This mAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Immunogen: Recombinant human protein was used as the immunogen for the TLR2 antibody.
Storage: Store the TLR2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
