Description
TLR2 Antibody | F44371-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This anti-TLR2 antibody is available for research use only.
Purity: Purified
Description: TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Immunogen: A portion of amino acids 720-749 from the mouse protein was used as the immunogen for this anti-TLR2 antibody.
Storage: Aliquot the anti-TLR2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
