TLR2 Antibody | F44370-0.08ML

TLR2 Antibody | F44370-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, FACS, ELISA

Buffer: N/A

Limitation: This TLR2 antibody is available for research use only.

Purity: Purified

Description: TLR2 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]

Immunogen: A portion of amino acids 212-242 from the human protein was used as the immunogen for this TLR2 antibody.

Storage: Aliquot the TLR2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.