Description
TLE1 Antibody | V3890-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: TLEP1-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P, WB
Buffer: N/A
Limitation: This TLE1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. [UniProt]
Immunogen: A portion of amino acids 175-338 from the human protein was used as the immunogen for the TLE1 antibody.
Storage: Store the TLE1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
