Description
TLE1 Antibody | F40324-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 381CT18.5.1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This TLE1 antibody is available for research use only.
Purity: Purified
Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Immunogen: A portion of amino acids 199-228 from the human protein was used as the immunogen for this TLE1 antibody.
Storage: Aliquot the TLE1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
