Tissue Factor Antibody / F3 / CD142 | RQ5414

Tissue Factor Antibody / F3 / CD142 | RQ5414 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: GGE-6

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This Tissue Factor antibody is available for research use only.

Purity: Affinity purified

Description: The F3 gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [RefSeq]

Immunogen: A synthetic peptide specific to human Tissue Factor / F3 was used as the immunogen for the Tissue Factor antibody.

Storage: Store the Tissue Factor antibody at -20 °C.