Description
TIMP1 Antibody | F54350-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IF, WB, IHC-P
Buffer: N/A
Limitation: This TIMP-1 antibody is available for research use only.
Purity: SAS precipitation
Description: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Immunogen: A portion of amino acids 157-188 from the human protein was used as the immunogen for the TIMP-1 antibody.
Storage: Aliquot the TIMP-1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
