TIE2 Antibody | F50680-0.4ML

TIE2 Antibody | F50680-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, WB, ELISA

Buffer: N/A

Limitation: This TIE2 antibody is available for research use only.

Purity: Purified

Description: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Immunogen: A portion of amino acids 758-789 from the human protein was used as the immunogen for this TIE2 antibody.

Storage: Aliquot the TIE2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.