Thyroid Stimulating Hormone Receptor / TSHR Antibody (beta chain) | R32688

Thyroid Stimulating Hormone Receptor / TSHR Antibody (beta chain) | R32688 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse, Rat

Application: WB

Buffer: Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Limitation: This TSH Receptor antibody is available for research use only.

Purity: Antigen affinity

Description: TSHR (Thyroid-Stimulating Hormone Receptor), also called LGR3, is mapped to 14q31.1. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

Immunogen: Amino acids 515-538 (ITLERWYAITFAMRLDRKIRLRHA) from the beta subunit of the human protein were used as the immunogen for the TSH Receptor antibody.

Storage: After reconstitution, the TSH Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.