Thioredoxin Antibody / TRX / TXN | F54201-0.05ML

Thioredoxin Antibody / TRX / TXN | F54201-0.05ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 1850CT339.14.1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This Thioredoxin antibody is available for research use only.

Purity: Protein G purified

Description: Thioredoxin / TRX / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Immunogen: Recominant human Thioredoxin protein was used as the immunogen for the Thioredoxin antibody.

Storage: Aliquot the Thioredoxin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.