TGFBR2 Antibody | F41742-0.08ML

TGFBR2 Antibody | F41742-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC, IF, ELISA

Buffer: N/A

Limitation: This TGFBR2 antibody is available for research use only.

Purity: Antigen affinity

Description: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Immunogen: A portion of amino acids 13-40 from the human protein was used as the immunogen for this TGFBR2 antibody.

Storage: Aliquot the TGFBR2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.