Description
TGFBR2 Antibody | F41742-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, IF, ELISA
Buffer: N/A
Limitation: This TGFBR2 antibody is available for research use only.
Purity: Antigen affinity
Description: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Immunogen: A portion of amino acids 13-40 from the human protein was used as the immunogen for this TGFBR2 antibody.
Storage: Aliquot the TGFBR2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
