Description
TGFBR1 Antibody / TGF beta Receptor I | RQ6526 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, Direct ELISA
Buffer: Lyophilized from 1X PBS with 2% Trehalose
Limitation: This TGF-beta receptor type-1 antibody is available for research use only.
Purity: Affinity purified
Description: Transforming growth factor, beta receptor I is a TGF beta receptor. TGFBR1 is its human gene. The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). TGFB1 regulates cell cycle progression by a unique signaling mechanism that involves its binding to TGFBR2 and activation of TGFBR1. Both are transmembrane serine/threonine receptor kinases.
Immunogen: An E. coli-derived human protein (amino acids L34-K490) was used as the immunogen for the TGF-beta receptor type-1 antibody.
Storage: After reconstitution, the TGF-beta receptor type-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
