Description
Tff2 Antibody / Trefoil factor 2 | V8112-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: GE16C
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA
Buffer: N/A
Limitation: This TFF2 antibody is available for research use only.
Purity: PEG precipitation
Description: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.
Immunogen: A synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 protein was used as the immunogen for this TFF2 antibody.
Storage: Store the TFF2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
