Description
TFAP2B Polyclonal Antibody | E-AB-66159 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Application: WB
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Background: This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human TFAP2B (NP_003212.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purification
Dilution: WB 1:500-1:2000
Conjugation: Unconjugated
Calculated Molecular Weight: 50 kDa/51 kDa
Observed Molecular Weight: 45 kDa
Clonality: N/A
