Description
TCF/LEF Luciferase Reporter Lentivirus (Wnt/β-catenin Signaling Pathway) | 79787 | Gentaur US, UK & Europe Disrtribition
Category: Cell Line/Lentiviruses
Application: • Screen for activators or inhibitors of Wnt signaling pathway in the transduced target cells • Generation of TCF/LEF luciferase reporter stable cell line
Background: N/A
Description: The TCF/LEF Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene under the control of TCF/LEF-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the Wnt/β-catenin signaling pathway in the target cells can be monitored by measuring the luciferase activity.
Product Type: Lentivirus
Shippement Condition: -80°C