TBX1 Antibody | F54472-0.4ML

TBX1 Antibody | F54472-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P, WB, IF

Buffer: N/A

Limitation: This TBX1 antibody is available for research use only.

Purity: Antigen affinity purified

Description: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Immunogen: A portion of amino acids 327-356 from the human protein was used as the immunogen for the TBX1 antibody.

Storage: Aliquot the TBX1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.