TBP Antibody (TATA Binding Protein) | F52225-0.4ML

TBP Antibody (TATA Binding Protein) | F52225-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 830CT4.3.3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat, Monkey

Application: IHC-P, WB, ELISA

Buffer: N/A

Limitation: This TBP antibody is available for research use only.

Purity: Purified

Description: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Immunogen: Purified His-tagged protein was used to produced this monoclonal TBP antibody.

Storage: Aliquot the TBP antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.