Tbk1 Antibody | F45532-0.4ML

Tbk1 Antibody | F45532-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This Tbk1 antibody is available for research use only.

Purity: Antigen affinity

Description: Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

Immunogen: A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody.

Storage: Aliquot the Tbk1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.