Tau Monoclonal Antibody | E-AB-22141

Tau Monoclonal Antibody | E-AB-22141 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Application: WB, IHC-p

Research Area: Cancer, Neuroscience, Signal Transduction

Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide of Tau

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Protein A purification

Dilution: WB 1:1000-2000, IHC 1:100-200

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: 79 kDa

Clonality: Monoclonal