TAU Antibody (MAPT) | F47898-0.08ML

TAU Antibody (MAPT) | F47898-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, IF, ELISA

Buffer: N/A

Limitation: This TAU antibody is available for research use only.

Purity: Purified

Description: TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]

Immunogen: A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.

Storage: Aliquot the TAU antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.