Description
TAK1 Antibody / MAP3K7 | RQ4734 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: ACHF-13
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human, Mouse
Application: IF/ICC, WB
Buffer: N/A
Limitation: This TAK1 antibody is available for research use only.
Purity: Affinity purified
Description: The protein encoded by the MAP3K7 gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Immunogen: A synthetic peptide specific to human MAP3K7/TAK1 was used as the immunogen for the TAK1 antibody.
Storage: Store the TAK1 antibody at -20 °C.
