TAK1 Antibody / MAP3K7 | RQ4734

TAK1 Antibody / MAP3K7 | RQ4734 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: ACHF-13

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human, Mouse

Application: IF/ICC, WB

Buffer: N/A

Limitation: This TAK1 antibody is available for research use only.

Purity: Affinity purified

Description: The protein encoded by the MAP3K7 gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.

Immunogen: A synthetic peptide specific to human MAP3K7/TAK1 was used as the immunogen for the TAK1 antibody.

Storage: Store the TAK1 antibody at -20 °C.