TAG-72 Antibody Cocktail | V2364IHC-7ML

TAG-72 Antibody Cocktail | V2364IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: B72.3 + CA72/733

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This TAG-72 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 antibody with a GCDFP-15 antibody is valuable in the diagnosis of apocrine carcinoma.

Immunogen: The membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and TAG-72 protein (CA72/733) were used as the immunogens for this antibody cocktail.

Storage: Store the TAG-72 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).