Description
Tadalafil | 27657-3 | Gentaur US, UK & Europe Disrtribition
Category: Phosphodiesterase/Inhibitors / Activators
Application: N/A
Background: Tadalafil is a small-molecule inhibitor of phosphodiesterase 5 (PDE5), a predominant PDE in the pulmonary vasculature that hydrolyzes cyclic guanosine monophosphate (cGMP) and is involved in the pathobiology of pulmonary arterial hypertension (PAH). Although it is used for the treatment of erectile dysfunction through oral administration, tadalafil also improves the vasoconstrictive-predominate condition of PAH through elevating cGMP levels in pulmonary vessels resulted from PDE5 inhibition.
Description: Tadalafil, also known as IC351 or Cialis, is a potent, reversible and competitive small-molecule inhibitor of PDE5
Product Type: Inhibitor
Shippement Condition: Room temp. (continental US) or gel packs
