Description
Sus scrofa CD3 epsilon&CD3 delta Heterodimer Protein, His Tag&Tag Free (MALS verified) | CDD-S52W3-50ug| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: Sus scrofa CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (CDD-S52W3) is expressed from human 293 cells (HEK293). It contains AA Glu 23 - Leu 116 (CD3E) & Tyr 22 - Leu 104 (CD3D) (Accession # NP_999392.1 (CD3E) & NP_998940.1 (CD3D) ).
Format: Powder.
Tag: C-10×His | Native.
Expression System: HEK293.
Expression Region: Glu 23 - Leu 116 (CD3E) & Tyr 22 - Leu 104 (CD3D).
Conjugate: Unconjugated.
Molecular Weight: 16.2 kDa (CD3E) & 13.5 kDa (CD3D).
Characteristics: Sus scrofa CD3E&CD3D Heterodimer Protein, His Tag&Tag Free is produced by co-expression of CD3E and CD3D, has a calculated MW of 16.2 kDa (CD3E) and 13.5 kDa (CD3D). Subunit CD3E is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag and subunit CD3G contains no tag at the C-terminus. As a result of glycosylation, the protein migrates as 19-22 kDa under reducing (R) condition, and 35-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE).
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
