Description
Survivin Antibody / BIRC5 | N1087-25UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: 1X PBS, pH 7.4
Limitation: This Survivin antibody is available for research use only.
Purity: Protein A affinity chromatography
Description: Survivin, also called BIRC5, is a protein encoded by the human BIRC5 gene. It is a member of the IAP (inhibitor of apoptosis family. Survivin binds to the active form of Caspase-3 and -7, effector or executioner caspases, preventing them from continuing the apoptosis-signaling cascade. Expression is regulated by p53, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level.
Immunogen: A recombinant protein fragment from human Survivin was used as the immunogen for this antibody.
Storage: Aliquot the antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
