SUMO2/3 Antibody | F42027-0.08ML

SUMO2/3 Antibody | F42027-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: IF, WB, IHC, ELISA

Buffer: N/A

Limitation: This SUMO2/3 antibody is available for research use only.

Purity: Purified

Description: SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

Immunogen: A portion of amino acids 49-81 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.

Storage: Aliquot the SUMO2/3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.