Description
Steroidogenic Factor 1 Antibody / SF-1 / NR5A1 | V8731-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: NR5A1/3397
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This NR5A1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Immunogen: A portion of amino acids 220-461 from the human protein was used as the immunogen for the NR5A1 antibody.
Storage: Store the NR5A1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
