Steroidogenic Factor 1 Antibody / SF-1 / NR5A1 | V8731-100UG

Steroidogenic Factor 1 Antibody / SF-1 / NR5A1 | V8731-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: NR5A1/3397

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This NR5A1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.

Immunogen: A portion of amino acids 220-461 from the human protein was used as the immunogen for the NR5A1 antibody.

Storage: Store the NR5A1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).