Steroidogenic Factor 1 Antibody / SF-1 / NR5A1 | V4016SAF-100UG

Steroidogenic Factor 1 Antibody / SF-1 / NR5A1 | V4016SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: rNR5A1/4369

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG1, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant Steroidogenic Factor 1 antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development. SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.

Immunogen: A portion of amino acids 220-461 from the human protein was used as the immunogen for the recombinant Steroidogenic Factor 1 antibody.

Storage: Aliquot the recombinant Steroidogenic Factor 1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Nucleus