Description
STAT1 Antibody | R30259 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This STAT1 antibody is available for research use only.
Purity: Antigen affinity
Description: Chen et al.(1998) determined the crystal structure of the DNA complex of a 67-kD core fragment of the Signal Transducer and Activator of Transcription 1 homodimer, lacking only the N-domain and the C-terminal transcriptional activation domain, at 2.9-angstrom resolution. Phosphorylation of STAT1 was also decreased in rheumatoid arthritis lymphocytes. It plays a key role in immunity against mycobacterial and viral infections. Activation of the STAT pathway is important in fibroblast growth factor (FGF) modulation of chondrocyte proliferation and endochondral bone formation during embryogenesis.
Immunogen: Amino acids 364-378 (FDKDVNERNTVKGFR-human) were used as the immunogen for this STAT1 antibody.
Storage: After reconstitution, the STAT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
