StAR Antibody / Steroidogenic acute regulatory protein | V8103-100UG

StAR Antibody / Steroidogenic acute regulatory protein | V8103-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: STAR/2077

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This StAR antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

Immunogen: A recombinant human partial protein (amino acids 39-108) was used as the immunogen for this StAR antibody.

Storage: Store the StAR antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).