Description
Squalene synthase Antibody / SQS / FDFT1 | F54769-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This Squalene synthase antibody is available for research use only.
Purity: Purified
Description: FDFT1 / Squalene synthase catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
Immunogen: A portion of amino acids 140-170 from the human protein was used as the immunogen for the Squalene synthase antibody.
Storage: Aliquot the Squalene synthase antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
