Spike Trimer (S1+S2) (K417T, E484K, N501Y), His- Tag (SARS-CoV-2) | 100988-1

Spike Trimer (S1+S2) (K417T, E484K, N501Y), His- Tag (SARS-CoV-2) | 100988-1 | Gentaur US, UK & Europe Disrtribition

Category: Coronavirus/Protein

Application: N/A

Background: N/A

Description: Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein contains three mutations: K417T, E484K and N501Y that have been found in emerging SARS-CoV-2 Variants of Concern and may lead to higher transmissibility and infectivity. This mutant Spike Trimer will be useful for structure-function studies, testing of neutralizing antibodies, or antibody and drug screening.   The construct also contains a C-terminal His-tag. Note that the expected MW of the S1+S2 monomer is 136kDa but migrates at a higher MW in SDS-PAGE due to glycosylation. The recombinant protein is ?90% pure following affinity purification.

Product Type: Protein

Shippement Condition: -80°C