Description
SPIB Antibody | N1035-25UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB
Buffer: 1X PBS, pH 7.4
Limitation: This SPIB antibody is available for research use only.
Purity: Protein A affinity chromatography
Description: SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.
Immunogen: A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.
Storage: Aliquot and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
