SPIB Antibody | N1035-100UG

SPIB Antibody | N1035-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB

Buffer: 1X PBS, pH 7.4

Limitation: This SPIB antibody is available for research use only.

Purity: Protein A affinity chromatography

Description: SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.

Immunogen: A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.

Storage: Aliquot and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.