Description
Spartin Antibody / SPART | RQ6684 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Rat
Application: WB, FACS, Direct ELISA
Buffer: Lyophilized from 1X PBS with 2% Trehalose
Limitation: This Spartin antibody is available for research use only.
Purity: Antigen affinity purified
Description: Spartin is a protein that in humans is encoded by the SPART gene. This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Immunogen: Recombinant human protein (amino acids H205-V631) was used as the immunogen for the Spartin antibody.
Storage: After reconstitution, the Spartin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
