SOX2 Antibody | R31408

SOX2 Antibody | R31408 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC-P

Buffer: N/A

Limitation: This SOX2 antibody is available for research use only.

Purity: Antigen affinity

Description: SRY (sex determining region Y)-box 2 is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. The protein is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. It was found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. It is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, it has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.

Immunogen: Amino acids 171-183 (YSMMQDQLGYPQH) were used as the immunogen for this SOX2 antibody.

Storage: After reconstitution, the SOX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.