SOX2 Antibody | F52993-0.08ML

SOX2 Antibody | F52993-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This anti-SOX2 antibody is available for research use only.

Purity: Antigen affinity

Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Immunogen: This anti-SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.

Storage: Aliquot the anti-SOX2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.