Sox17 Antibody | F52803-0.4ML

Sox17 Antibody | F52803-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This Sox17 antibody is available for research use only.

Purity: Antigen affinity

Description: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

Immunogen: This Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17.

Storage: Aliquot the Sox17 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.