Description
SORBS2 Antibody / ARGBP2 | F54906-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, IHC-P, FACS
Buffer: N/A
Limitation: This SORBS2 antibody is available for research use only.
Purity: Purified
Description: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
Immunogen: A portion of amino acids 175-204 from the human protein was used as the immunogen for the SORBS2 antibody.
Storage: Aliquot the SORBS2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
