SOCS7 Antibody | F45339-0.08ML

SOCS7 Antibody | F45339-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This SOCS7 antibody is available for research use only.

Purity: Antigen affinity

Description: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Immunogen: A portion of amino acids 458-486 from the human protein was used as the immunogen for this SOCS7 antibody.

Storage: Aliquot the SOCS7 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.