Description
SNCA Polyclonal Antibody | E-AB-36111 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC-p, ELISA
Research Area: Cancer, Neuroscience
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from the Internal region of human Synuclein-α.
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 14 kDa
Observed Molecular Weight: 15 kDa
Clonality: Polyclonal
