Description
SMMHC Antibody Cocktail (Smooth Muscle Myosin Heavy Chain) | V2752-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: MYH11/923 + SMMS-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Rat
Application: FACS, IF, IHC-P
Buffer: N/A
Limitation: This SMMHC antibody cocktail is available for research use only.
Purity: Protein G affinity chromatography
Description: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Immunogen: Recombinant human protein (MYH11/923) and human uterus extract (SMMS-1) were used as the immunogen for the SMMHC antibody cocktail.
Storage: Store the SMMHC antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
