SIRT6 Antibody | F54008-0.1ML

SIRT6 Antibody | F54008-0.1ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 50% Glycerol and 0.03% ProClin 300

Format: Purified

Clone: 6C9-D10-D3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat, Primate

Application: WB, ICC/IF, IP

Buffer: N/A

Limitation: This SIRT6 antibody is available for research use only.

Purity: Protein G affinity

Description: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]

Immunogen: A human recombinant protein was used as the immunogen for this SIRT6 antibody.

Storage: Store the SIRT6 antibody at -20 °C.