Description
SIRT1 Antibody | F52857-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: IHC, IF, WB, ELISA
Buffer: N/A
Limitation: This SIRT1 antibody is available for research use only.
Purity: Antigen affinity
Description: SIRT1 is a NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. [UniProt]
Immunogen: A portion of amino acids 566-601 of the mouse protein was used as the immunogen for the SIRT1 antibody.
Storage: Store at 4oC for up to one month. For long term, aliquot the SIRT1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
