Description
SIRPα / HEK293 Recombinant Cell Line | 60689 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Cell Line
Application: This cell line is useful for SIRPα:CD47 protein binding analyses and screening for antibodies or inhibitors of CD47.
Background: SIRPα (CD172A, PTPNS1) is a member of the signal-regulatory-protein (SIRP) family, which are transmembrane immunoglobulin receptors that negatively regulate receptor tyrosine kinase-coupled signaling processes. SIRPα is expressed predominantly on macrophages and dendritic cells. Interaction with its ligand CD47 mediates signals that blocks phagocytosis (also known as the "don't eat me" signal).
Description: Recombinant HEK293 cell constitutively expressing full length human SIRPα (#NM_080792). Surface expression is confirmed by flow cytometry.
Product Type: Cell Line
Shippement Condition: -80°C
