Description
SHP1 (PTPN6) Fluorogenic Assay Kit | 79831 | Gentaur US, UK & Europe Disrtribition
Category: Protein Phosphatase/Assay Kit
Application: Great for studying enzyme kinetics and HTS applications.
Background: SHP1 (also known as PTPN6) is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine-stimulated cells. The noncatalytic N-terminus of this phosphatase can interact with MAP kinases and negatively regulates ERK2 and p38 MAP-kinases activity. The PTPN6 is involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating molecules related to the MAP kinase pathway.
Description: The Fluorogenic SHP1 Assay Kit is designed to measure SHP1 activity for screening and profiling applications, in a homogeneous assay with no timeconsuming washing steps. This kit is developed to identify inhibitors of the regulatory region of SHP1.
Product Type: Assay Kit
Shippement Condition: -80°C
