Serotonin transporter Antibody | R30795

Serotonin transporter Antibody | R30795 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Rat

Application: WB, IHC-P

Buffer: N/A

Limitation: This Serotonin transporter antibody is available for research use only.

Purity: Antigen affinity

Description: SLC6A4 (Solute carrier family 6, member 4), also known as SERT (Serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.

Immunogen: An amino acid sequence from the N-terminus of rat Serotonin transporter (NSQKVLSECKDREDCQEN) was used as the immunogen for this Serotonin transporter antibody.

Storage: After reconstitution, the Serotonin transporter antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.