Description
SERBP1 Antibody / PAI-RBP1 | V8456-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: SERBP1/3492
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This PAI-RBP1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: PAI-RBP1 / SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
Immunogen: A portion of amino acids 3-139 from the human protein was used as the immunogen for the PAI-RBP1 antibody.
Storage: Store the PAI-RBP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
